James thomson 1998

James thomson scientist biography pdf Thomson graduated with a B. Kelly, Janet. This professorship has not only allowed Thomson to collaborate in an interdisciplinary research initiative, but has also provided access to marine organisms, which are important to his interest in the evolution of pluripotency. Igor Slukvin, a professor of pathology and laboratory medicine who is leading the clinical trials, will be the lead investigator of the artery project after Thomson retires.

James Thomson (cell biologist)

American developmental biologist

For other people named James Thomson, see James Thomson (disambiguation).

James Alexander Thomson is an American developmental biologist best known for deriving the first human embryonic stem cell line in [1] and for deriving human induced pluripotent stem cells (iPS) in [2]

Research

Human embryonic stem cells [which are cells that reproduce over and over and over again until they eventually die.

they are what other cells 'stem' from] can divide without limit, and yet maintain the potential to make all the cells of the body. This remarkable potential makes them useful for basic research on the function of the human body, for drug discovery and testing, and as a source of cells and tissues for transplantation medicine. In , Thomson's Lab was the first to report the successful isolation of human embryonic stem cells.

On November 6, , Science published this research in an article titled "Embryonic Stem Cell Lines Derived from Human Blastocysts", results which Science later featured in its “Scientific Breakthrough of the Year” article, [3]

In spite of their great medical potential, however, human embryonic stem cells generated enormous controversy because their derivation involved the destruction of a human embryo.

In , Thomson's group (contemporaneously with Dr. Shinya Yamanaka) reported a method for converting human skin cells into cells that very closely resemble human embryonic stem cells. Published in Science in late in an article titled "Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells", the results garnered international attention for potentially ending the ethical controversy surrounding human embryonic stem cell research.[4][2] Science later featured induced pluripotent stem cells in its “Scientific Breakthrough of the Year” article, [5]

Education

Thomson graduated with a B.S.

in biophysics from the University of Illinois in He entered the Veterinary Medical Scientist Training Program at the University of Pennsylvania, receiving his doctorate in veterinary medicine in , and his doctorate in molecular biology in His doctoral thesis involved understanding genetic imprinting in early mammalian development under the mentorship of Davor Solter at the Wistar Institute.

Thomson also spent two years (–91) as a postdoctoral research fellow in the Primate In Vitro Fertilization and Experimental Embryology Laboratory at the Oregon National Primate Research Center, and completed a residency in veterinary pathology at the University of Wisconsin–Madison (–).

Millikan scientist Morgridge Institute for Research. Arizona State University. In fact, he believes that iPS cells provide a whole realm of possibilities due to the relative ease of creating and cultivating iPS cells compared to pluripotent stem cells derived from embryos, which may be difficult to obtain. Human embryonic stem cells [which are cells that reproduce over and over and over again until they eventually die.

He joined the Wisconsin Regional (now National) Primate Research Center on campus as its chief pathologist in There, he became the first in the world to successfully isolate and culture nonhuman primate embryonic stem cells. This led to his human embryonic stem cell discovery in [6]

Current employment

He serves as Director of Regenerative Biology at the Morgridge Institute for Research in Madison, Wisconsin, is a professor in the Department of Cell and Regenerative Biology at the University of Wisconsin School of Medicine and Public Health and a professor in the Molecular, Cellular, and Developmental Biology Department at the University of California, Santa Barbara.[7] He is also a founder of Cellular Dynamics International, a Madison-based company producing derivatives of human induced pluripotent stem cells for drug discovery and toxicity testing.[8][9][10]

Awards

Thomson is a member of the National Academy of Sciences and the recipient of numerous awards and prizes.

In , Thomson received the Golden Plate Award of the American Academy of Achievement.[11] He was on the cover of TIME magazine's "America's Best in Science & Medicine" feature in for his work with human embryonic stem cells,[12] and again in when the magazine named him one of the world's most influential people for his derivation of human induced pluripotent stem cells.[13] In , Thomson was co-recipient, with Dr.

Shinya Yamanaka, of the King Faisal International Prize and the Albany Medical Center Prize. In , Thomson received an honorary doctor of science degree from the University of Illinois at Urbana-Champaign.[14] He also won the McEwen Award for Innovation from the International Society for Stem Cell Research.[15]

References

  1. ^"Embryonic Stem Cell Lines Derived from Human Blastocysts", Science, November 6,
  2. ^ abYu, J.; Vodyanik, M.

    A.; Smuga-Otto, K.; Antosiewicz-Bourget, J.; Frane, J. L.; Tian, S.; Nie, J.; Jonsdottir, G. A.; Ruotti, V.; Stewart, R.; Slukvin, I. I.; Thomson, J. A. (21 December ). "Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells". Science. (): – BibcodeSciY.

  3. Rutherford scientist
  4. James thomson scientist biography facts
  5. Dalton scientist

    6. doi/science PMID&#; S2CID&#;

  6. ^"Breakthrough of the Year: Capturing the Promise of Youth", Vogel, G., Science , ,
  7. ^Kolata, Gina (22 November ). "Man who helped start stem cell war may end it". The New York Times. Retrieved 5 September
  8. ^"Breakthrough of the Year: Reprogramming Cells", Vogel, G., Science , ,
  9. ^"A starring role for nonhuman primates in the stem cell story".
  10. ^"UCSB Snags 'Father of Stem-Cell Research' Jamie Thomson Setting Up Shop in SB", Santa Barbara Independent, April 20,
  11. ^"Cellular Dynamics International".
  12. ^"TR Engineered Stem Cells; Mimicking human disease in a dish", The Technology Review, May/June
  13. ^"New Stem Cells Will Reduce the Need for Animal Testing", The Times, May 4,
  14. ^"Golden Plate Awardees of the American Academy of Achievement".

    . American Academy of Achievement.

  15. ^Golden Ferderic (August 20, ).

    James thomson scientist biography Still based in Madison and employing nearly people, the company manufactures cell lines derived from pluripotent stem cells for myriad applications across scientific research and health care. Contents move to sidebar hide. May 1, Prior to that time, stem cells were only successfully isolated in rodents.

    "Cellular Biology: Stem Winder". Time.

  16. ^Wilmut, Ian (May 12, ). "Shinya Yamanaka & James Thomson". Time.
  17. ^"Commencement ceremonies to take place May 12 at Illinois". News Bureau. University of Illinois.

    James thomson scientist biography wikipedia The third leap was in , with the discovery of adult pluripotent stem cells, which offered a way of coaxing adult skin cells back to an original blank state. That fact is playing out today. Arizona State University. Contents move to sidebar hide.

    May 1,

  18. ^"ISSCR Award for Innovation". . Retrieved

External links